HNPP

HNPP - Hereditary Neuropathy with liability to Pressure Palsies - is an inherited nerve disease which affects the peripheral motor (muscle) and sensory nerves.

It causes recurrent episodes of numbness and weakness brought on by minor pressure or trauma. Recovery from these episodes is usually complete at first, but may progress to only a partial recovery.

Symptoms of HNPP may be similar to Charcot-Marie-Tooth disease, and the condition is sometimes referred to as HSMN.

This page lists useful links provided by Jon Leonard, the founder of the HNPP UK website. To visit his website, please visit the following link:


Please note, that because some of the information below is from non-UK websites, some of the tests and treatments may vary to those offered in this country.


General links

Written by Maureen Horton RN and Dr. G. Parry, this website is a good starting point for anyone who suspects they have HNPP or is newly-diagnosed with the condition:


Taken from the Charcot-Marie-Tooth Association website, this article is written by Maureen Horton and edited by Dr. Phillip Chance, the CMTA Medical Advisory Board:



CMT World website

The Cmtworld website has various articles that try to put HNPP into the wider context of Charcot-Marie-Tooth and HMSN:

Numbness in Charcot-Marie-Tooth disease by Dr Gareth J. Parry, M.D. Neurologist


The basics of Charcot-Marie-Tooth disease by Linda Crabtree, founder of CMT International


Diagnosing Charcot-Marie-Tooth disease by Dorothy B. Gosling, Reg. N.



The following links may also be of some interest:



The Jack Miller Center for Peripheral Neuropathy

This center was established in May 2001 as a part of The University of Chicago's Division of Biological Sciences. It is committed to educating the public and healthcare providers about peripheral neuropathy, providing state-of-the-art care to patients affected by the condition, and contributing to basic and clinical research in an effort to identify the causes and potential cures for these disorders.

Its website features a short but fairly comprehensive article on HNPP:



Medical links

The Neuromuscular Disease Centre at Washington University, St. Louis, USA features the following information:


The National Center for Biotechnological Information features this page about HNPP:


The Athena Diagnostics US Genetic testing labs website includes this useful page:


The Hospital Practice website features this information about Charcot-Marie-Tooth disease, written by James R. Lupski:



Email groups

Here are two email groups that people with Charcot-Marie-Tooth disease, HSMN or HNPP may find useful:


Return to the Charcot-Marie-Tooth disease/HMSN page.