Minicore myopathy is a congenital myopathy. This group of conditions mainly affect the proximal - shoulder, upper arm, pelvic and thigh - muscles causing weakness and wasting. The condition was originally named 'multicore myopathy', however the preferred term is now 'minicore myopathy'. The names refer to the abnormal structure of the affected muscle fibres when they are examined under a microscope.

Symptoms of the condition become obvious in the foetus or within the first three years of life. These include reduced foetal movement, floppiness, motor delay and respiratory complications. The condition is generally non- or slowly progressive and affected children are able to walk eventually.

Most cases are sporadic, with no previous family history, although autosomal recessive and autosomal dominant patterns of inheritance have been seen.

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